Last update
3/21/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 5 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Iron (elemental) (from 180 mg Ferrous Bisglycinate)(Ferrochel™)
36 mg
200%
Top Medical Research Studies
8
We conducted a study to discover how intravenous iron therapy impacts sleep apnea in patients suffering from heart failure, anemia, and iron deficiency. Patients were randomly assigned to receive either ferric carboxymaltose or a placebo to assess changes in their sleep and respiratory function after treatment.
Our findings revealed that the intravenous iron treatment significantly improved the hypercapnic ventilatory response, which is the way our bodies react to increased carbon dioxide levels. We observed that, in particular, patients who received iron saw a notable reduction in their apneas and hypopneas—those moments when breathing stops or becomes shallow while asleep. Specifically, the apnoea-hypopnoea index dropped to an average of 12 events per hour with treatment, compared to 19 events per hour in the placebo group.
Furthermore, those who received iron also reported better overall symptoms and had improved physical capacity during exercise tests. This suggests that iron therapy not only helps with sleep-related breathing issues but may also boost oxygen delivery during physical activities.
Overall, our study supports the notion that iron therapy could play an important role in managing sleep apnea among patients with heart failure, providing them with enhanced breathing during sleep and better quality of life.
Our findings revealed that the intravenous iron treatment significantly improved the hypercapnic ventilatory response, which is the way our bodies react to increased carbon dioxide levels. We observed that, in particular, patients who received iron saw a notable reduction in their apneas and hypopneas—those moments when breathing stops or becomes shallow while asleep. Specifically, the apnoea-hypopnoea index dropped to an average of 12 events per hour with treatment, compared to 19 events per hour in the placebo group.
Furthermore, those who received iron also reported better overall symptoms and had improved physical capacity during exercise tests. This suggests that iron therapy not only helps with sleep-related breathing issues but may also boost oxygen delivery during physical activities.
Overall, our study supports the notion that iron therapy could play an important role in managing sleep apnea among patients with heart failure, providing them with enhanced breathing during sleep and better quality of life.
Read More
Most Useful Reviews
9
Eased restless legs
My husband suffers from restless leg syndrome, so I took this since I was advised it could help with iron deficiency. After taking one before bed, he was able to sleep well.
Read More
9
Quality sleep restored
I take one capsule at night before bed. My sleep is now of high quality; I fall asleep quickly and wake easily. I've had sleep issues related to my thyroid problems and found this supplement effective without affecting my thyroid. It’s a fantastic remedy!
Read More
7.5
Improved sleep quality
1 people found this helpful
About two weeks! At first, I thought it wouldn’t work, but after a fortnight, I realised my sleep was improving significantly.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We conducted a study to discover how intravenous iron therapy impacts sleep apnea in patients suffering from heart failure, anemia, and iron deficiency. Patients were randomly assigned to receive either ferric carboxymaltose or a placebo to assess changes in their sleep and respiratory function after treatment.
Our findings revealed that the intravenous iron treatment significantly improved the hypercapnic ventilatory response, which is the way our bodies react to increased carbon dioxide levels. We observed that, in particular, patients who received iron saw a notable reduction in their apneas and hypopneas—those moments when breathing stops or becomes shallow while asleep. Specifically, the apnoea-hypopnoea index dropped to an average of 12 events per hour with treatment, compared to 19 events per hour in the placebo group.
Furthermore, those who received iron also reported better overall symptoms and had improved physical capacity during exercise tests. This suggests that iron therapy not only helps with sleep-related breathing issues but may also boost oxygen delivery during physical activities.
Overall, our study supports the notion that iron therapy could play an important role in managing sleep apnea among patients with heart failure, providing them with enhanced breathing during sleep and better quality of life.
Our findings revealed that the intravenous iron treatment significantly improved the hypercapnic ventilatory response, which is the way our bodies react to increased carbon dioxide levels. We observed that, in particular, patients who received iron saw a notable reduction in their apneas and hypopneas—those moments when breathing stops or becomes shallow while asleep. Specifically, the apnoea-hypopnoea index dropped to an average of 12 events per hour with treatment, compared to 19 events per hour in the placebo group.
Furthermore, those who received iron also reported better overall symptoms and had improved physical capacity during exercise tests. This suggests that iron therapy not only helps with sleep-related breathing issues but may also boost oxygen delivery during physical activities.
Overall, our study supports the notion that iron therapy could play an important role in managing sleep apnea among patients with heart failure, providing them with enhanced breathing during sleep and better quality of life.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Eased restless legs
My husband suffers from restless leg syndrome, so I took this since I was advised it could help with iron deficiency. After taking one before bed, he was able to sleep well.
Read More
9
Quality sleep restored
I take one capsule at night before bed. My sleep is now of high quality; I fall asleep quickly and wake easily. I've had sleep issues related to my thyroid problems and found this supplement effective without affecting my thyroid. It’s a fantastic remedy!
Read More
7.5
Improved sleep quality
1 people found this helpful
About two weeks! At first, I thought it wouldn’t work, but after a fortnight, I realised my sleep was improving significantly.
Read More
9
Better sleep routine
It helps me sleep well. I take it at night, and it gradually helps me unwind.
Read More
7.5
Sleep improved
1 people found this helpful
It tastes like blood, so I drink it while holding my breath. Since starting the iron supplements, my sleep quality has improved noticeably.
Read More
Frequently Asked Questions
7.5
Improved sleep quality
1 people found this helpful
About two weeks! At first, I thought it wouldn’t work, but after a fortnight, I realised my sleep was improving significantly.
9
Better sleep routine
It helps me sleep well. I take it at night, and it gradually helps me unwind.
9
Eased restless legs
My husband suffers from restless leg syndrome, so I took this since I was advised it could help with iron deficiency. After taking one before bed, he was able to sleep well.
9
Quality sleep restored
I take one capsule at night before bed. My sleep is now of high quality; I fall asleep quickly and wake easily. I've had sleep issues related to my thyroid problems and found this supplement effective without affecting my thyroid. It’s a fantastic remedy!
8
We conducted a study to discover how intravenous iron therapy impacts sleep apnea in patients suffering from heart failure, anemia, and iron deficiency. Patients were randomly assigned to receive either ferric carboxymaltose or a placebo to assess changes in their sleep and respiratory function after treatment.
Our findings revealed that the intravenous iron treatment significantly improved the hypercapnic ventilatory response, which is the way our bodies react to increased carbon dioxide levels. We observed that, in particular, patients who received iron saw a notable reduction in their apneas and hypopneas—those moments when breathing stops or becomes shallow while asleep. Specifically, the apnoea-hypopnoea index dropped to an average of 12 events per hour with treatment, compared to 19 events per hour in the placebo group.
Furthermore, those who received iron also reported better overall symptoms and had improved physical capacity during exercise tests. This suggests that iron therapy not only helps with sleep-related breathing issues but may also boost oxygen delivery during physical activities.
Overall, our study supports the notion that iron therapy could play an important role in managing sleep apnea among patients with heart failure, providing them with enhanced breathing during sleep and better quality of life.
Our findings revealed that the intravenous iron treatment significantly improved the hypercapnic ventilatory response, which is the way our bodies react to increased carbon dioxide levels. We observed that, in particular, patients who received iron saw a notable reduction in their apneas and hypopneas—those moments when breathing stops or becomes shallow while asleep. Specifically, the apnoea-hypopnoea index dropped to an average of 12 events per hour with treatment, compared to 19 events per hour in the placebo group.
Furthermore, those who received iron also reported better overall symptoms and had improved physical capacity during exercise tests. This suggests that iron therapy not only helps with sleep-related breathing issues but may also boost oxygen delivery during physical activities.
Overall, our study supports the notion that iron therapy could play an important role in managing sleep apnea among patients with heart failure, providing them with enhanced breathing during sleep and better quality of life.
References
- Caravita S, Faini A, Vignati C, Pelucchi S, Salvioni E, et al. Intravenous iron therapy improves the hypercapnic ventilatory response and sleep disordered breathing in chronic heart failure. Eur J Heart Fail. 2022;24:1940. 10.1002/ejhf.2628
Data last updated:
